Panousis et al., J Lipid Res 2001
:
Finally, TGF-beta was also demonstrated to inhibit the IFN-gamma mediated down-regulation of ABC-1 Wang et al., Arterioscler Thromb Vasc Biol 2002
(Arteriosclerosis) :
Interferon-gamma mediated downregulation of cholesterol efflux and ABC1 expression is by the Stat1 pathway ... In the present study, the pathway by which IFN-gamma inhibited ABC1 expression was investigated with signal transducers and activators of transcription ( Stat1 ) knockout mice
Hastie et al., J Biol Chem 2008
(Neoplasm Invasiveness...) :
IFNgamma induced calpain expression and activation and increased the phosphorylation and degradation of the calpain substrate ABCA1 in 1542CP3TX cancer cells
Hao et al., Atherosclerosis 2009
(Atherosclerosis) :
In the present study, we have investigated the effect of IFN-gamma on ABCA1 expression and cholesterol efflux in THP-1 macrophage derived foam cells ... Furthermore, AG-490 and STAT1 siRNA almost compensated the effect of IFN-gamma on ABCA1 expression and cholesterol efflux