Gene interactions and pathways from curated databases and text-mining

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ADAMTS5 — IRF6

Text-mined interactions from Literome

Ellman et al., Gene 2012 (Intervertebral Disc Degeneration) : In bovine NP cells, MyD88i potently antagonizes LPS- or IL-1 mediated induction of cartilage degrading enzyme production, including MMP-1, MMP-13, ADAMTS-4, and ADAMTS-5
Ko et al., Biomaterials 2013 (Osteoarthritis) : Treatment with SFN-PLGA microspheres inhibited the mRNA and protein expression of COX-2, ADAMTS-5 and MMP-2 induced by LPS in articular chondrocytes