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ADAMTS5 — IRF6
Text-mined interactions from Literome
Ellman et al., Gene 2012
(Intervertebral Disc Degeneration) :
In bovine NP cells, MyD88i potently antagonizes
LPS- or IL-1 mediated
induction of cartilage degrading enzyme production, including MMP-1, MMP-13, ADAMTS-4, and
ADAMTS-5
Ko et al., Biomaterials 2013
(Osteoarthritis) :
Treatment with SFN-PLGA microspheres inhibited the mRNA and protein expression of COX-2,
ADAMTS-5 and MMP-2
induced by
LPS in articular chondrocytes