Pooler et al., Neurosci Lett 2004
:
Direct activation of adenylate cyclase with forskolin also increased APP expression
Clark et al., J Cyclic Nucleotide Res 1978
:
The effects of unpurified APP ( NH ) P on adenylate cyclase activity closely resembled the effects of guanylylimidodiphosphate ( GPP ( NH ) P ) ; that is, APP ( NH ) P alone caused a time dependent, quasi-irreversible activation, and the stimulation of adenylate cyclase by APP ( NH ) P in combination with epinephrine was synergistic, eliminating the need for GTP