Gene interactions and pathways from curated databases and text-mining

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AGRP — PRL

Text-mined interactions from Literome

Schioth et al., Neuroreport 2001 : We studied the effect of Agrp ( agouti related peptide ) on LH ( luteinizing hormone ) and PRL ( prolactin ) surges in ovariectomized rats primed with estradiol and progesterone
Xiao et al., Endocrinology 2003 : We have therefore examined the effects of AGRP on the HPA axis and on prolactin (PRL) at baseline and in response to stimulation by IL-1 beta in nine ovariectomized rhesus monkeys ... There was a significant stimulatory effect of 50 microg AGRP on ACTH ( P < 0.001 ), cortisol ( P < 0.001 ), and PRL ( P < 0.001 ) release over time ... In conclusion, AGRP stimulated ACTH, cortisol, and PRL release in the monkey and enhanced the ACTH response to IL-1 beta
Langouche et al., J Neuroendocrinol 2004 : Agouti related protein ( AgRP ( 83-132 ) ), a known endogenous MC3R and MC4R antagonist, did not reduce the stimulation of prolactin mRNA expression by gamma3-MSH or Ala ( 8 ) -gamma2-MSH ... On its own, AgRP ( 83-132 ) significantly increased prolactin mRNA expression level and prolactin accumulation