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ALB — IL2
Text-mined interactions from Literome
Kowalski-Saunders et al., Hepatology 1992
:
Pure interleukin-1,
interleukin-6 and tumor necrosis factor-alpha also
inhibited albumin synthesis ( p less than 0.05, Wilcoxon 's rank sum test, n = 5 ), interleukin-6 having the greatest effect
Li et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006
(Carcinoma, Hepatocellular...) :
IL-6 but not
IL-2 and IL-10
suppressed the production of hepatic
albumin in vitro
Schultz et al., J Natl Cancer Inst 1992
(Lymphoma, T-Cell...) :
In normal mice,
IL-2 caused a dose dependent increase of both radiolabeled MAb and
albumin in the spleen, liver, lung, and lymph node, but it spared the brain
Mier et al., J Immunol 1987
(Liver Neoplasms, Experimental) :
IL 2 in concentrations from 1 to 1000 U/ml
had no effect on the synthesis of factor B or
albumin ; conversely, there was a dose dependent increase in the rate of synthesis of factor B and decrease in albumin synthesis mediated by culture supernatants of IL 2-activated PBMNC
Thorpe et al., Br J Haematol 1989
(Hemophilia A) :
Immunoglobulin and
albumin products did not
inhibit IL-2 secretion to any significant extent, but factor IX concentrates were inhibitory
Rothschild et al., Hepatology 1988
(Disease...) :
Likewise, the inverse relation between acute-phase protein synthesis and
albumin synthesis
regulated by
interleukin 1 and other cytokines will merit further study