Gene interactions and pathways from curated databases and text-mining

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ALB — IL2

Text-mined interactions from Literome

Kowalski-Saunders et al., Hepatology 1992 : Pure interleukin-1, interleukin-6 and tumor necrosis factor-alpha also inhibited albumin synthesis ( p less than 0.05, Wilcoxon 's rank sum test, n = 5 ), interleukin-6 having the greatest effect
Li et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2006 (Carcinoma, Hepatocellular...) : IL-6 but not IL-2 and IL-10 suppressed the production of hepatic albumin in vitro
Schultz et al., J Natl Cancer Inst 1992 (Lymphoma, T-Cell...) : In normal mice, IL-2 caused a dose dependent increase of both radiolabeled MAb and albumin in the spleen, liver, lung, and lymph node, but it spared the brain
Mier et al., J Immunol 1987 (Liver Neoplasms, Experimental) : IL 2 in concentrations from 1 to 1000 U/ml had no effect on the synthesis of factor B or albumin ; conversely, there was a dose dependent increase in the rate of synthesis of factor B and decrease in albumin synthesis mediated by culture supernatants of IL 2-activated PBMNC
Thorpe et al., Br J Haematol 1989 (Hemophilia A) : Immunoglobulin and albumin products did not inhibit IL-2 secretion to any significant extent, but factor IX concentrates were inhibitory
Rothschild et al., Hepatology 1988 (Disease...) : Likewise, the inverse relation between acute-phase protein synthesis and albumin synthesis regulated by interleukin 1 and other cytokines will merit further study