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ARF1 — VEGFA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA) → ARF1/GDP complex (ARF1) (modification, activates) Daher et al., J Biol Chem 2010*
  Evidence: mutant phenotype

Text-mined interactions from Literome

Martin et al., Invest Ophthalmol Vis Sci 2004 (Eye Abnormalities...) : In the HVS, Arf expression in perivascular cells may block their accumulation or repress Vegf expression to promote HVS involution and prevent PHPV
Ikeda et al., Circ Res 2005 (Ischemia) : Thus, ARF6 is involved in the temporal-spatial organization of caveolae/lipid rafts- and ROS dependent VEGF signaling in ECs as well as in angiogenesis in vivo