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ATG5 — IFNG
Text-mined interactions from Literome
Simon et al., Clin Transplant 2003
:
ATG induced decreases in the expression of
IFN-gamma , perforin, and granzyme B and increases in IL-10 and TGF-beta might be considered beneficial to the recipient, whereas increases in the expression of IL-7, IL-15, and TNF-alpha genes might be involved in immunological processes not effected by ATG that may harm the transplant in the long term
Bonnefoy-Berard et al., Cell Immunol 1992
:
The
ATG induced interleukin-2 (IL-2) and
interferon-gamma (IFN-gamma) gene expression and lymphokine secretion in cell culture supernatant and IL-2 receptor ( CD25 ) expression
Chang et al., J Biol Chem 2010
(Inflammation) :
Either
Atg5 ( -/- ) or Atg7 ( -/- ) MEFs are,
independent of changes in
IFN-gamma receptor expression, resistant to IFN-gamma activated Jak2-STAT1, which suggests that autophagy is important for IFN-gamma signal transduction
Hwang et al., Cell Host Microbe 2012
(Caliciviridae Infections) :
Nondegradative
role of
Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of
interferon gamma