Gene interactions and pathways from curated databases and text-mining

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ATP5O — CDC73

Text-mined interactions from Literome

Tsuyuki et al., Biochim Biophys Acta 2002 : As we had found previously that thapsigargin, an endomembrane Ca2+-ATPase inhibitor, induces production of intracellular platelet activating factor (PAF) [ Br. J. Pharmacol. 116 ( 1995 ) 2141 ], we decided to investigate the possible roles of intracellular PAF in nuclear factor (NF)-kappaB activation of thapsigargin stimulated rat peritoneal macrophages
Catalán et al., Neurosci Res 1994 : In the present study, experiments were conducted to determine the effect of platelet activating factor (PAF) on ( Na+, K+ ) -ATPase in rat cerebral cortex ... Omission of external calcium caused an increase in the basal activity and abolished the PAF effect on ( Na+, K+ ) ATPase ... The present study demonstrates that PAF inhibits ( Na+, K+ ) ATPase activity in the cerebral cortex and suggests that PAF released during certain pathological conditions, such as ischemia, may act on ATPase
Hu et al., Sheng Li Xue Bao 1996 : ( 3 ) Activity of Ca ( 2+ ) -ATPase could be inhibited by exogenous PAF ... ( 4 ) The inhibitory effect of PAF on PASMCs Ca ( 2+ ) -ATPase could be reversed by verapamil
Itadani et al., Prostaglandins Other Lipid Mediat 1998 : To assess its intracellular activity, the effect of PAF on Na+, K ( + ) -ATPase was examined in dog submandibular gland cells ... PAF inhibited Na+, K ( + ) -ATPase in membrane preparations, and the inhibitory effect was dependent on the protein concentration in the enzyme preparation ... Kinetic analysis of PAF inhibition of Na+, K ( + ) -ATPase suggests that the inhibition of Na+, K ( + ) -ATPase by PAF is not due to competition by PAF at K ( + ) - or Na ( + ) -binding sites on the enzyme, but by complex inhibitory mechanisms