Gene interactions and pathways from curated databases and text-mining

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ATP7A — IL6

Text-mined interactions from Literome

Rowlett et al., Am J Physiol Gastrointest Liver Physiol 2008 (Crohn Disease...) : MNK inhibition also blocked IL-6 but permitted IL-10 production in response to LPS
Patel et al., Biometals 2013 : Neocuproine, but not ATP7A deficiency, reduced the production of FGF-9, IL-1a, IL-12p70, IL-2, IL-3, IL-4, IL-6 , MIP-1ß, MIP-2, RANTES, and TNFa
Fukunaga et al., EMBO J 1997 : Further, MNK1 was activated upon stimulation of HeLa cells with 12-O-tetradecanoylphorbol-13-acetate, fetal calf serum, anisomycin, UV irradiation, tumor necrosis factor-alpha, interleukin-1beta , or osmotic shock, and the activation by these stimuli was differentially inhibited by the MEK inhibitor PD098059 or the p38 MAP kinase inhibitor SB202190