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AZU1 — IL6
Text-mined interactions from Literome
Kou et al., J Periodontol 2008
:
Immortalized human gingival epithelial cells were stimulated with P. gingivalis membrane vesicles, and the
effects of
HBP on mRNA expression of cyclooxygenase (COX)-2,
interleukin (IL)-6 and -8, and matrix metalloproteinase (MMP)-1 and -3 were examined using real-time reverse transcription-polymerase chain reaction ...
HBP inhibited the mRNA expression of COX-2,
IL-6 and -8, and MMP-1 and -3 in a dose dependent manner, whereas epigallocatechin gallate ( a control polyphenol ) inhibited COX-2 mRNA expression only
Schou et al., Innate Immun 2011
:
Using a human monocyte cell line, we have shown that lipopolysaccharide (LPS) triggered secretion of
IL-6 is
enhanced up to 10-fold when full-length
HBP or the peptide are present in low-to-moderate concentrations