Gene interactions and pathways from curated databases and text-mining

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AZU1 — IL6

Text-mined interactions from Literome

Kou et al., J Periodontol 2008 : Immortalized human gingival epithelial cells were stimulated with P. gingivalis membrane vesicles, and the effects of HBP on mRNA expression of cyclooxygenase (COX)-2, interleukin (IL)-6 and -8, and matrix metalloproteinase (MMP)-1 and -3 were examined using real-time reverse transcription-polymerase chain reaction ... HBP inhibited the mRNA expression of COX-2, IL-6 and -8, and MMP-1 and -3 in a dose dependent manner, whereas epigallocatechin gallate ( a control polyphenol ) inhibited COX-2 mRNA expression only
Schou et al., Innate Immun 2011 : Using a human monocyte cell line, we have shown that lipopolysaccharide (LPS) triggered secretion of IL-6 is enhanced up to 10-fold when full-length HBP or the peptide are present in low-to-moderate concentrations