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Uzzo et al., Clin Cancer Res 2002 (Prostatic Neoplasms) : In this study, we demonstrate by immunoblotting and immunohistochemistry that physiological levels of zinc inhibit activation of nuclear factor (NF)-kappa B transcription factor in PC-3 and DU-145 human prostate cancer cells, reduce expression of NF-kappa B-controlled antiapoptotic protein c-IAP2 , and activate c-Jun NH ( 2 ) -terminal kinases
Cartier et al., J Biol Chem 2011 : Cellular inhibitor of apoptosis protein-1 ( cIAP1 ) can regulate E2F1 transcription factor mediated control of cyclin transcription