Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Langenfeld et al., Mol Cancer Res 2005 (Cell Transformation, Neoplastic) : We show that BMP-2 induces the phosphorylation of mTOR in A549 and H1299 lung cancer cell lines, which is attenuated by the PI3K antagonists LY-294002 and wortmannin
Wahdan-Alaswad et al., Mol Cancer Res 2012 (Prostatic Neoplasms) : Intriguingly, silencing raptor alone enhanced, whereas silencing rictor repressed, the phosphorylation of Smad1/5, indicating that mTORC1 represses, whereas mTORC2 activates , BMP signaling