Gene interactions and pathways from curated databases and text-mining

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BTRC — IL6

Text-mined interactions from Literome

Gyotoku et al., Arch Dermatol Res 2001 : Some IL-6 family cytokines enhanced the production of stem cell factor (SCF) , a potent mast cell growth factor, from NIH/3T3 fibroblasts, but the amount of SCF produced by NIH/3T3 fibroblasts was not paralleled by the mast cell growth-enhancement induced by the IL-6 family cytokines
Ren et al., J Clin Invest 2003 : In vitro studies using primary mouse hepatocytes demonstrate that SCF causes hepatocyte proliferation and is induced by IL-6 and that treatment with anti-SCF antibodies inhibits IL-6 induced hepatocyte proliferation
Neta et al., J Immunol 1994 : SCF , unlike IL-1 does not induce hemopoietic CSFs and IL-6 or gene expression of a scavenging mitochondrial enzyme manganese superoxide dismutase in the bone marrow, suggesting that SCF and IL-1 radioprotect by distinct pathways
Tisdale et al., Blood 1998 : Stem cell factor (SCF)/granulocyte colony stimulating factor ( G-CSF ) -mobilized and CD34 enriched PB cells were divided into two equal aliquots and transduced with one of two retroviral vectors carrying the neomycin-resistance gene ( neo ) for 4 days in the presence of interleukin-3 (IL-3), IL-6 , and SCF in the first 5 animals, IL-3/IL-6/SCF/Flt-3 ligand (FLT) in 2 subsequent animals, or IL-3/IL-6/SCF/FLT plus an autologous stromal monolayer ( STR ) in the final 2