Gene interactions and pathways from curated databases and text-mining

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CALCA — IL7

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CALCA → IL7 (increases)
    Evidence: The multinuclear cells formed after IL-7 stimulation was found to increase the expression of calcitonin, an authentic marker for human osteoclasts by 200 fold.

Text-mined interactions from Literome

Fernandez et al., Cell Immunol 2003 : Calcitonin gene related peptide indirectly inhibits IL-7 responses in pre-B cells by induction of IL-6 and TNF-alpha in bone marrow
Aida et al., Ann Rheum Dis 1994 (Arthritis, Rheumatoid) : Calcitonin inhibits production of immunoglobulins, rheumatoid factor and interleukin-1 by mononuclear cells from patients with rheumatoid arthritis