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AKT1 — CAT
Text-mined interactions from Literome
Ushio-Fukai et al., J Biol Chem 1999
(Hypertrophy) :
Furthermore, diphenylene iodonium, an inhibitor of flavin containing oxidases, or overexpression of
catalase to block angiotensin II-induced intracellular H ( 2 ) O ( 2 ) production significantly
inhibits angiotensin II-induced
Akt/PKB phosphorylation, indicating a role for ROS in agonist induced Akt/PKB activation
Jang et al., Cell Signal 2005
:
Interestingly, there was PI3K dependent activation of
AKT , p70S6K, JNKs, and NF-kappaB in
response to
catalase
Venkatesan et al., J Cell Physiol 2007
:
Furthermore, expression of dominant negative
Akt and constitutively active FoxO1
increased catalase transcription, respectively
Yi et al., Nutrition 2010
(Hypertension...) :
No differences in superoxide dismutase and glutathione peroxidase activities were observed between SHRSPs and SHRs. Clofibrate treatment significantly upregulated renal HMGCS2 expressions,
inhibited phosphorylation of
Akt , and decreased malondialdehyde levels and
catalase activities in SHRSP kidney tissues ( P < 0.05 )
Saunders et al., Free Radic Biol Med 2010
(Ovarian Neoplasms) :
Akt phosphorylation was also
inhibited by
PEG-catalase and apocynin
Li et al., PloS one 2013
:
Furthermore, we found that the presence of NAC, as well as the overexpression of MnSOD, could almost completely abolish the activation of
Akt , extracellular-signal regulated kinase ( Erk ) 1/2, c-Jun N-terminal kinase (JNK), and p38, although only JNK and p38 were
affected by overexpression of
catalase