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CCL2 — PTK2
Text-mined interactions from Literome
Bian et al., Exp Eye Res 2003
(Translocation, Genetic) :
These results suggest that activation of DEX-sensitive, CSA-resistant MEK/ERK and p38 pathways, and activation of NF-kappaB, PKC, and
PTK are
essential for IL-8 and
MCP-1 expression by hRPE cells
Zeng et al., Acta Pharmacol Sin 2005
:
Inhibitors of PKC ( calphostin C, 50-500 nmol/L and RO-31-8220, 10-100 nmol/L ), CaM ( W7, 28-280 micromol/L ), ERK1/2 MAPK ( PD 98059, 2-20 micromol/L ), p38 MAPK ( SB 203580, 0.6-6 micromol/L ), JNK MAPK ( curcumin, 2-10 micromol/L ), and NF-kappaB ( PDTC, 10-100 nmol/L ) markedly reduced Hcy 100 micromol/L induced production of MCP-1 and IL-8 in human cultured whole blood, but the inhibitors of
PTK ( genistein, 2.6-26 micromol/L and tyrphostin, 0.5-5 micromol/L )
had no obvious effect on
MCP-1 and IL-8 production
Wang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2006
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
This study was aimed to explore the expression of MIP-1alpha, MCP-1 and their receptors CCR-1, CCR-2 in bcr/abl fusion gene positive CML cells, and to study the
effects of P210 ( bcr/abl ) fusion
protein tyrosine kinase on expression of MIP-1alpha,
MCP-1 and their receptors CCR-1, CCR-2 mRNAs in chronic myeloid leukemia cells
Rovin et al., Kidney Int 1994
:
The structurally distinct
protein tyrosine kinase ( PTK ) inhibitors genistein, herbimycin A, and tyrphostin each
caused a dose dependent inhibition of the effects of IL-1 on mesangial
MCP-1 activity