Gene interactions and pathways from curated databases and text-mining

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CD5 — IL10

Text-mined interactions from Literome

Gary-Gouy et al., Blood 2002 (Calcium Signaling...) : Introducing CD5 into CD5 ( - ) B cells induces the production of IL-10 by activating its promoter and the synthesis of its mRNA
Bouaziz et al., Immunol Rev 2008 (Autoimmune Diseases...) : We have labeled this specific subset of regulatory B cells as B10 cells to highlight that these rare CD1d ( hi ) CD5 ( + ) B cells only produce IL-10 and are responsible for most IL-10 production by B cells and to distinguish them from other regulatory B-cell subsets that may also exist
Spencer et al., Int Immunol 1997 : A role for IL-12 in the aging process was suggested when it was found that recombinant IL-12 ( rIL-12 ) directly stimulated splenic CD5+ B cells to secrete IL-10 , and both CD5+ and CD5- B cells could be directly induced to produce IL-6 in response to rIL-12