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CD5 — IL10
Text-mined interactions from Literome
Gary-Gouy et al., Blood 2002
(Calcium Signaling...) :
Introducing
CD5 into CD5 ( - ) B cells
induces the production of
IL-10 by activating its promoter and the synthesis of its mRNA
Bouaziz et al., Immunol Rev 2008
(Autoimmune Diseases...) :
We have labeled this specific subset of regulatory B cells as B10 cells to highlight that these rare CD1d ( hi )
CD5 ( + ) B cells only produce IL-10 and are
responsible for most
IL-10 production by B cells and to distinguish them from other regulatory B-cell subsets that may also exist
Spencer et al., Int Immunol 1997
:
A role for IL-12 in the aging process was suggested when it was found that recombinant IL-12 ( rIL-12 ) directly stimulated splenic CD5+ B cells to secrete
IL-10 , and both
CD5+ and CD5- B cells could be directly
induced to produce IL-6 in response to rIL-12