Gene interactions and pathways from curated databases and text-mining

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CDH1 — MMP13

Text-mined interactions from Literome

Mei et al., Carcinogenesis 2002 : The sum effect of MMP inhibitors demonstrated that NO-induced activation of MMP may cause the degradation of E-cadherin and the subsequent dissociation of beta-catenin, thereby contributing to the cytosolic accumulation of beta-catenin and nuclear formation of beta-catenin/LEF-1 complex
Nawrocki-Raby et al., Am J Pathol 2003 (Bronchial Neoplasms...) : E-Cadherin mediates MMP down-regulation in highly invasive bronchial tumor cells
Wang et al., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2004 (Lymphatic Metastasis...) : In the group of nasopharyngeal carcinoma with distant metastasis, the expression of E-cadherin and nm23H1 also increased and the expression of CD44H, MMP-3 and VEGF all increased
Zhao et al., Cancer Lett 2013 (Neovascularization, Pathologic...) : EA also reversed epithelial to mesenchymal transition by up-regulating E-cadherin and inhibiting the expression of Snail, MMP-2 and MMP-9