Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Lau et al., PloS one 2013 (Neoplasm Invasiveness...) : The pharmacological inhibition of phosphatidylinositol-3-kinase (PI3K), mammalian target of rapamycin (mTOR), and MEK suggests that both PI3K/Akt/mTOR and MAPK/ERK signaling are required for FGF2 induced E-cadherin down-regulation
Maru et al., J Urol 2013 (Carcinoma, Renal Cell...) : We investigated whether mTORC2 regulates E-cadherin expression and controls cell motility during HIF-2a down-regulation in renal cell carcinoma cells ... Results show that mTORC2 might regulate E-cadherin expression and suppress cell motility by controlling the mTORC2-HIF-2a signaling pathway