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CNTF — PRKAA1

Text-mined interactions from Literome

Steinberg et al., Endocrinology 2006 (Obesity) : Intracerebroventricular CNTF ( Ax15 ) reduced food intake, increased arcuate nucleus (ARC) signal transducer and activator of transcription 3 phosphorylation, and reduced AMPK signaling but not in the paraventricular nucleus ( PVN ), posterior hypothalamus, or cortex ... Both leptin and CNTF reduced AMPK activity and acetyl-coenzyme A carboxylase phosphorylation in the ARC and PVN of control fed mice ... A HFD blunted leptin but not CNTF effects on AMPK signaling in the ARC and PVN
Escartin et al., J Neurosci 2007 : CNTF significantly increased the phosphorylation level of the intracellular energy sensor AMP activated protein kinase (AMPK) , supporting a specific reorganization of brain energy pathways
Hu et al., Hepatology 2008 (Carcinoma, Hepatocellular...) : Furthermore, CNTF induced mitogen activated protein kinase ( MAPK ) activation suppresses AMPK activity in the early phase of CNTF stimulation
Steinberg et al., Diabetes 2009 (Obesity) : The effects of CNTF on skeletal muscle glucose uptake and AMPK/Akt signaling were investigated in incubated soleus and extensor digitorum longus (EDL) muscles from muscle-specific AMPKalpha2 kinase-dead, gp130 ( DeltaSTAT ), and lean and obese ob/ob and high-fat fed mice