◀ Back to INS

CRH — INS

Text-mined interactions from Literome

Cleare et al., J Clin Endocrinol Metab 2001 (Fatigue Syndrome, Chronic) : Looking at all subjects, 24-h urinary free cortisol was higher after active compared with placebo treatments, but 0900-h cortisol levels and the ACTH and cortisol responses to human CRH and the insulin stress test did not differ
Rohner-Jeanrenaud et al., Endocrinology 1992 (Obesity) : The early transient stimulatory effect of CRF on plasma insulin levels could not be prevented by the prior administration of an anti-CRF serum or the alpha-helical CRF- ( 9-41 ) antagonist, although administration of either one of these compounds was effective in preventing the CRF induced changes in the pituitary-adrenal axis ... The effect of CRF on the early insulin response was, however, completely suppressed by an acute cholinergic blockade ( i.v. injection of atropine )
Grino et al., Endocrinology 1992 (Hypoglycemia) : We previously reported that insulin induced hypoglycemia (IIH) induces a large increase in plasma ACTH and corticosterone levels in the developing rat during the stress hyporesponsive period and that this effect is mediated , at least partially, by arginine vasopressin (AVP), but not corticotropin releasing factor
Huang et al., J Mol Endocrinol 2006 (Body Weight...) : The present results suggest opposite effects of insulin and corticosterone deficiency on the hypophysiotropic CRF and the CRF1R mRNA contents, whereas the expression of CRF2R was mostly related to insulin, but not to the corticosterone status
O'Carroll et al., J Endocrinol 2008 : Vasopressin potentiates corticotropin releasing hormone induced insulin release from mouse pancreatic beta-cells ... Activation of the endogenously expressed M3 receptor by the cholinergic agonist carbachol also potentiated CRH induced insulin secretion, indicating that the phenomenon may be pathway specific ( i.e. Ca2+-phospholipase C ) rather than agonist specific ... The protein kinase C ( PKC ) inhibitors Ro-31-8425 and bisindolylmaleimide I attenuated the potentiating effect of AVP on CRH stimulated insulin secretion and blocked AVP stimulated insulin secretion ... Additionally, no AVP potentiation of CRH stimulated insulin secretion was observed upon incubation in Ca2+-free Krebs-Ringer buffer
Schmid et al., Proc Natl Acad Sci U S A 2011 (Insulinoma) : CRH stimulated both cellular content and release of insulin in rat islet and insulinoma cells
Murat et al., Mol Endocrinol 2012 (Second Messenger Systems) : Vasopressin ( AVP ) and CRH synergistically regulate adrenocorticotropin and insulin release at the level of the pituitary and pancreas, respectively
Tomori et al., J Clin Endocrinol Metab 1989 (Hypoglycemia) : Adrenergic modulation of adrenocorticotropin responses to insulin induced hypoglycemia and corticotropin releasing hormone ... To study possible adrenergic modulation of pituitary-adrenal responses to insulin induced hypoglycemia and CRH we examined the effect of nonselective alpha-blockade ( phentolamine ) and nonselective beta-blockade ( propranolol ) on plasma ACTH, cortisol, and vasopressin ( AVP ) responses to hypoglycemia and CRH in five normal men
Koide et al., J Clin Endocrinol Metab 1986 (Addison Disease...) : The primary lesion site in isolated ACTH deficiency was studied in three patients by examining the responses of immunoreactive ACTH to insulin induced hypoglycemia, lysine vasopressin, and synthetic ovine corticotropin releasing hormone (CRH)
Karlsson et al., Acta Endocrinol (Copenh) 1988 : Effects of corticotropin releasing hormone on insulin and glucagon secretion in mice ... Thus, CRH slightly affects basal plasma levels of insulin and glucagon in mice ... In contrast, stimulated insulin and glucagon secretions are not affected by CRH
Moltz et al., Am J Physiol 1985 : Corticotropin releasing factor inhibits insulin release from perfused rat pancreas ... Release of insulin and glucagon into the perfusate was measured in the presence and absence of CRF ( 0.1, 1, and 10 ng/ml ) under conditions of normal and high glucose concentration ( 5.5 and 11 mM ) ... Under both conditions, CRF ( 0.1, 1, and 10 ng/ml ) induced a rapid, dose dependent inhibition of insulin release followed by a remarkable postinhibitory rebound when exposure to CRF was discontinued
Torres-Aleman et al., Peptides 1984 : Stimulation of insulin secretion by corticotropin releasing factor (CRF) in anesthetized rats ... These results suggest that CRF may play a modulatory role in insulin secretion ; however, whether CRF acts directly on the beta-cell or through some CRF stimulated mediator remains to be established
Suemaru et al., Nihon Naibunpi Gakkai Zasshi 1995 (Hypoglycemia) : On the 50th day of therapy, the i.v. infusion of glucose quickly produced moderate hyperglycemia and an increase in plasma insulin , and inhibited secretions of CRH , ACTH and cortisol
Notsu et al., Endocr J 1994 (Brain Neoplasms...) : Laboratory data showed low plasma adrenocorticotrophin ( ACTH ) and cortisol levels with blunted responses to insulin induced hypoglycemia and corticotrophin releasing factor (CRF)
Oh et al., Am J Physiol 1994 (Body Weight...) : The present study examined whether leucine induced insulin secretion is also impaired in CRF and investigated the cellular derangements for such a potential abnormality
Ichinose et al., Intern Med 1996 (Hypogonadism...) : Prolonged and exaggerated responses of adrenocorticotropin ( ACTH ) to insulin induced hypoglycemia and corticotropin releasing hormone (CRH) were also noted
Motoyoshi et al., Diabetologia 1998 (Adenoma...) : Glibenclamide, KCl or corticotropin releasing factor (CRF) stimulated ( p < 0.05 ) insulin secretion both in AtT20HI and AtT20HI-GLUT2-GK-6 cells