Kook et al., Mol Biol Cell 2000
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Considering that Cas associates with FAK, paxillin, and other molecules involved in the integrin signaling pathway, these results suggest that caspase mediated cleavage of Cas contributes to the disassembly of focal adhesion complexes and interrupts survival signals from the extracellular matrix
Hoon Kim et al., Biochem Biophys Res Commun 2003
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We previously demonstrated caspase mediated cleavage of p130cas during apoptosis and identified two caspase-3 cleavage sites [ 1 ]