Gene interactions and pathways from curated databases and text-mining

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EGFR — IL13

Text-mined interactions from Literome

Allahverdian et al., Am J Respir Cell Mol Biol 2008 : Moreover, exogenous IL-13 enhanced epithelial repair and induced epidermal growth factor receptor (EGFR) phosphorylation ... IL-13 induced EGFR phosphorylation and the IL-13-reparative effect on AEC are mediated via HB-EGF ... Finally, we demonstrated that inhibition of EGFR tyrosine kinase activity by tyrphostin AG1478 increases IL-13 release after injury, suggesting negative feedback between EGFR and IL-13 during repair
Lowry et al., Am J Respir Cell Mol Biol 2008 (Asthma...) : In contrast, IL-13 induced airway epithelial cell mucous cell hyperplasia, mucin and mucin related gene expression, epidermal growth factor receptor mRNA, and epidermal growth factor receptor activation along with airway hyperreactivity in WT mice but not in GGT ( enu1 ) mice
Wu et al., J Neurosurg 2010 (Brain Injuries...) : Simvastatin modified the caveolin-1 expression in lipid rafts in astrocyte cell membrane, suppressed the phosphorylation of EGFR in lipid rafts of astrocytes after OGD, and inhibited the OGD induced interleukin-1 production