Gene interactions and pathways from curated databases and text-mining

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EGFR — PRKAG1

Text-mined interactions from Literome

Liu et al., Cell cycle (Georgetown, Tex.) 2009 (Breast Neoplasms) : At the molecular level, metformin increases P-AMPK , reduces P-EGFR, EGFR , P-MAPK, P-Src, cyclin D1 and cyclin E ( but not cyclin A or B, p27 or p21 ), and induces PARP cleavage in a dose- and time dependent manner
Jung et al., J Cell Physiol 2010 (Neoplasms) : Quercetin suppresses HeLa cell viability via AMPK induced HSP70 and EGFR down-regulation ... Together, these results suggest that quercetin may have anti-tumor effects on HeLa cells via AMPK induced HSP70 and down-regulation of EGFR
He et al., Biochem Biophys Res Commun 2013 (Glioblastoma) : Gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells