Gene interactions and pathways from curated databases and text-mining

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EGFR — TCF23

Text-mined interactions from Literome

Nagel-Wolfrum et al., Mol Cancer Res 2004 (Neoplasms) : The transcription factor signal transducer and activator of transcription ( Stat ) 3 is activated through the interleukin-6 family of cytokines and by binding of growth factors to the epidermal growth factor (EGF) receptor
Tao et al., Cell Signal 2004 : The Epstein-Barr virus ( EBV ) latent membrane protein 1 (LMP1) oncoprotein may cause multiple cellular changes including the induction of epidermal growth factor receptor (EGFR) expression and activation of the NFkappaB transcription factor
Tao et al., Virus Res 2004 : The Epstein-Barr virus ( EBV ) latent membrane protein 1 (LMP1) oncoprotein may cause multiple cellular changes, including the induction of epidermal growth factor receptor (EGFR) expression and the activation of the nuclear factor kappa B (NFkappaB) transcription factor
Stehr et al., J Pediatr Surg 2006 : In this study, we tested the role of the signal transducer and activator of transcription 1 ( STAT-1 ) as this transcription factor is activated by the EGFR and known to induce p21 expression
Ziv et al., J Cell Biochem 2008 (Inflammation...) : EGFR dependent activation resulted in the upregulation of the transcription factor , c-Fos, while the EGFR independent activation mode was of a shorter duration, did not affect c-Fos expression but induced IL-8 mRNA expression
Wilkinson et al., Assay Drug Dev Technol 2008 (MAP Kinase Signaling System) : Activation of cell surface receptors, such as epidermal growth factor receptor (EGFR) and cMET, upon ligand binding, leads to the activation of the downstream MAPK signaling pathway and transcription factor , activator protein 1 (AP1), which then induce the expression of genes that are important for cell growth and proliferation
RosanĂ² et al., Proc Natl Acad Sci U S A 2009 (Neoplasm Invasiveness...) : We then demonstrate that silencing of both beta-arrestin-1 and beta-arrestin-2 inhibits ET ( A ) R-driven signaling, causing suppression of Src, mitogen activated protein kinase ( MAPK ), AKT activation, as well as EGFR transactivation and a complete inhibition of ET-1 induced beta-catenin/TCF transcriptional activity and cell invasion
Miller et al., Mol Cell Biol 1998 : The Epstein-Barr virus latent membrane protein 1 (LMP1) oncoprotein causes multiple cellular changes, including induction of epidermal growth factor receptor (EGFR) expression and activation of the NF-kappaB transcription factor
Matsumoto et al., Life Sci 1998 : Epidermal growth factor receptor mediated expression of NF-kappaB transcription factor in osteoblastic MC3T3-E1 cells cultured under a low-calcium environment