Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Fingar et al., Mol Cell Biol 2004 : Here we demonstrate that restoration of mTOR signaling ( by using a rapamycin-resistant mutant of mTOR ) rescues rapamycin inhibited G ( 1 ) -phase progression, and restoration of signaling along the mTOR dependent S6K1 or 4E-BP1/eukaryotic translation initiation factor 4E ( eIF4E ) pathways provides partial rescue
Wang et al., Mol Cell Biol 2007 (Neoplasms) : Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase dependent and Mnk mediated eukaryotic translation initiation factor 4E phosphorylation