Gene interactions and pathways from curated databases and text-mining

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Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Csibi et al., PloS one 2010 : The translation regulatory subunit eIF3f controls the kinase dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse
Harris et al., EMBO J 2006 : mTOR dependent stimulation of the association of eIF4G and eIF3 by insulin ... Here, we present evidence that mTOR interacts directly with eIF3 and that mTOR controls the association of eIF3 and eIF4G ... This novel effect was blocked by rapamycin and other inhibitors of mTOR , and it required neither eIF4E binding to eIF4G nor eIF3 binding to the 40S ribosomal subunit