Gene interactions and pathways from curated databases and text-mining

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EPHB2 — SYK

Text-mined interactions from Literome

Slack et al., Eur J Immunol 2007 : Syk dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan
García-García et al., J Immunol 2009 : FcgammaRIIIB induced nuclear phosphorylation of ERK , and of Elk-1, was not affected by Syk , PI3K, or MEK inhibitors
Yang et al., Exp Cell Res 2012 (Diabetic Nephropathies...) : Syk inhibitors suppressed high glucose induced ERK activation, whereas U0126 had no effect on Syk activation
Jiang et al., J Exp Med 1998 : BCR mediated activation of ERK2, although maintained in Lyn-deficient cells, was abolished in Syk-deficient cells and partially inhibited in Btk-deficient cells, indicating that BCR mediated ERK2 activation requires Syk and that sustained ERK2 activation requires Btk