Gene interactions and pathways from curated databases and text-mining

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FGF1 — SOS1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Kulahin et al., Acta crystallographica. Section F, Structural biology and crystallization communications 2008 : This difference may be important for SOS mediated FGF1 dimerization in rat
Zhu et al., Structure 1993 : The SOS-FGF crystal structure is consistent with the model that SOS stabilizes FGF by neutralizing several positively charged residues that would destabilize the native structure by electrostatic repulsion
Kouhara et al., Cell 1997 : In this report, we describe the purification, cloning, and characterization of a novel protein, designated FRS2, that is tyrosine phosphorylated and binds to Grb2/Sos in response to FGF or NGF stimulation