Gene interactions and pathways from curated databases and text-mining

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FGF1 — VEGFA

Text-mined interactions from Literome

Wu et al., J Biol Chem 2000 : However, blockade of PKC diminished thymidine incorporation into DNA induced by VEGF but not FGF or EGF
Saadeh et al., Endocrinology 2000 : Furthermore, FGF-2 induced dose dependent increases in VEGF protein levels ( P < 0.01 ) ... In summary, FGF-2 induced VEGF expression by osteoblastic cells is a dose dependent event that may be independent of concomitant FGF-2 induced modulation of TGFbeta activity
Hajitou et al., Breast Cancer Res Treat 2000 (Breast Neoplasms) : Remarkably, FGF-4 but not FGF-3, stimulated the secretion of vascular endothelial growth factor ( VEGF165 ) without altering the steady-state level of its mRNA, suggesting a possible regulation of VEGF synthesis at the translational level in MCF7 cells
Inoue et al., Clin Cancer Res 2000 (Carcinoma, Transitional Cell...) : Vascular endothelial cell growth factor ( VEGF ) regulates angiogenesis and metastasis of bladder cancer ( transitional cell carcinoma, TCC ) through binding to VEGF receptor-2 (VEGFR-2)
Xu et al., J Thorac Cardiovasc Surg 2001 (Acute Disease...) : This study suggests that acute myocardial ischemia in patients results in increased expression of vascular endothelial growth factor but not fibroblast growth factor and that the functional activity of vascular endothelial growth factor receptors and that of other growth factors may be impaired
Chen et al., Cell Biol Int 2001 : Effect of FGF-1 and FGF-2 on VEGF binding to human umbilical vein endothelial cells
Scapini et al., J Immunol 2002 : Remarkably, affinity purified angiostatin kringle 1-3 fragments generated by neutrophils inhibited basic fibroblast growth factor plus vascular endothelial growth factor induced endothelial cell proliferation in vitro, and both vascular endothelial growth factor induced angiogenesis in the matrigel plug assay and fibroblast growth factor induced angiogenesis in the chick embryo chorioallantoic membrane assay, in vivo
Heryanto et al., Reproduction 2003 : These results demonstrate that endometrial angiogenesis after acute oestrogen treatment is primarily mediated by VEGF , but that under the influence of combined oestrogen and progesterone, FGF and PDGF are also probably involved
Carpenter et al., Circ Res 2003 (Anoxia...) : ET increases vascular endothelial cell growth factor ( VEGF ) production in vitro, and VEGF overexpression in the lung causes pulmonary edema in vivo
Hesling et al., J Invest Dermatol 2004 (Melanoma...) : We also demonstrate that : ( 1 ) among the major pro-angiogenic genes, FGF-2 was not increased before or after irradiation and vascular endothelial growth factor strongly inhibited after irradiation ; ( 2 ) expression of two important metalloproteinases, matrix metalloproteinase 2 and 9, involved in melanoma metastasis were decreased before and after irradiation ; ( 3 ) expression of their major inhibitor, tissue inhibitor of metalloproteinase, was mainly upregulated ; and ( 4 ) that invasion of BRCA1 downregulated cells was modified
Zaichuk et al., J Exp Med 2004 : It has been demonstrated that vascular endothelial cell growth factor ( VEGF ) induction of angiogenesis requires activation of the nuclear factor of activated T cells ( NFAT )
Horiguchi et al., Endocrine 2004 : Basic FGF and EGF did not modulate changes in VEGF-A mRNA levels after 4 and 24 h of treatment, but EGF increased VEGF-A significantly ( p < 0.05 ) after 96 h of treatment
Laschke et al., Hum Reprod 2006 (Endometriosis...) : Combined inhibition of vascular endothelial growth factor ( VEGF ), fibroblast growth factor and platelet derived growth factor, but not inhibition of VEGF alone, effectively suppresses angiogenesis and vessel maturation in endometriotic lesions
Shi et al., Pathology 2007 (Breast Neoplasms...) : Basic FGF augments hypoxia induced HIF-1-alpha expression and VEGF release in T47D breast cancer cells
Kashiwagi et al., Lab Invest 2011 (Lymphedema) : Interstitial tissue pressures in the distal areas of the tail wounds were markedly increased in Celecoxib+ with reduced expression of vascular endothelial cell growth factor ( VEGF ) -C. F4/80 positive cells were accumulated to the wound granulation tissues in Celecoxib-, and the accumulation of these cells was suppressed in Celecoxib+
Murakami et al., J Clin Invest 2011 (Ischemia) : FGF dependent regulation of VEGF receptor 2 expression in mice