Gene interactions and pathways from curated databases and text-mining

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FGF11 — IL6

Text-mined interactions from Literome

Fima et al., Eur Cytokine Netw 1999 (MAP Kinase Signaling System) : The effects of FGF and PDGF on IL-6 production were blocked in the presence of PKC inhibitors
Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta, FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2, COL2A1, CCL3, CCL4, CCL20, CXCL1, CXCL3, CXCL6, IL-1beta, IL-6 , and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Guerne et al., J Immunol 1990 : fibroblast growth factor , insulin growth factor-1 and 2, platelet growth factor or insulin, was able to significantly increase IL-6 synthesis
Chandrasekhar et al., J Cell Physiol 1989 : Induction of interleukin-1 receptors on chondrocytes by fibroblast growth factor : a possible mechanism for modulation of interleukin-1 activity
Iwamoto et al., Immunol Lett 1989 : Furthermore, interleukin 1 (IL-1) suppressed by 50-60 % the incorporation of [ 3H ] thymidine into DNA in high density chondrocyte cultures on plastic dishes in the presence of 10 % serum or fibroblast growth factor , although it increased twofold this incorporation in 0.3 % serum alone
Norioka et al., Jpn J Cancer Res 1994 (Neovascularization, Pathologic) : Interaction of interleukin-1 and interferon-gamma on fibroblast growth factor induced angiogenesis
Dooley et al., J Cell Physiol 1995 : Basic FGF did not reduce the levels of interleukin-6 (IL-6) , GM-CSF, or G-CSF released by steady state or IL-1 stimulated stroma
Berardi et al., Blood 1995 : To address the direct effects of FGF, we investigated whether FGF induced production of interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha, IL-6 , granulocyte colony stimulating factor, or granulocyte-macrophage colony stimulating factor by two types of accessory cells, bone marrow ( BM ) fibroblasts and macrophages