Gene interactions and pathways from curated databases and text-mining

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CDK2 — FGF2

Text-mined interactions from Literome

Aikawa et al., J Biol Chem 2001 (Chondrosarcoma) : In addition, the kinase activity of immunoprecipitated cyclin E or Cdk2 , assessed with retinoblastoma protein ( pRb ) as substrate, was dramatically reduced by FGF-2
Kokkinakis et al., J Neuropathol Exp Neurol 2004 (Cell Transformation, Neoplastic) : Western blot analyses demonstrated that MNU exposure caused progressive reduction of p21 protein levels, an increase of Rb phosphorylation, activation of AKT and CDK2 , and upregulation of FGF receptors
Kolupaeva et al., Cell cycle (Georgetown, Tex.) 2012 : In cells overexpressing cyclin D1/CDK4, FGF induced downregulation of cyclin E/CDK2 activity was absent
Murakami-Mori et al., J Immunol 1998 (Acquired Immunodeficiency Syndrome...) : Endogenous basic fibroblast growth factor is essential for cyclin E-CDK2 activity in multiple external cytokine induced proliferation of AIDS associated Kaposi 's sarcoma cells : dual control of AIDS associated Kaposi 's sarcoma cell growth and cyclin E-CDK2 activity by endogenous and external signals ... Thus, FGF actions are essential for cyclin E-CDK2 activity and S phase entry