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AKT1 — GAST

Text-mined interactions from Literome

Harris et al., Cancer Res 2004 (Adenocarcinoma...) : It is proposed that gastrin acting in an autocrine and endocrine manner via a CCK-2R isoform may activate PKB/Akt and that with expression of gastrin and CCK-2R isoforms increasing in BM samples, gastrin may aid progression of BM through amplification of antiapoptotic pathways ... It is proposed that gastrin acting in an autocrine and endocrine manner via a CCK-2R isoform may activate PKB/Akt and that with expression of gastrin and CCK-2R isoforms increasing in BM samples, gastrin may aid progression of BM through amplification of antiapoptotic pathways
Subramaniam et al., Gastroenterology 2008 (Adenocarcinoma...) : Gastrin mediated Akt activation was observed to be downstream of p38
Berna et al., J Biol Chem 2010 : Akt activation by CCK and gastrin could be inhibited by the PI3K inhibitor wortmannin
Min et al., J Pineal Res 2012 : Inhibitory effects of melatonin on the lipopolysaccharide induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt induced NF-?B and STAT/GAS activity