Gene interactions and pathways from curated databases and text-mining

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AKT2 — GNA13

Text-mined interactions from Literome

Wu et al., FEBS J 2006 : Finally, overexpression of the dominant negative mutant of RhoA blocked G alpha12QL- and G alpha13QL mediated inhibition, suggesting that activated G alpha12 and G alpha13 inhibit Akt signaling via RhoA ... Collectively, this study demonstrated the inhibitory effect of activated G alpha11, G alpha14, G alpha16, G alpha12 and G alpha13 on pro-survival Akt signaling
Chen et al., J Nat Med 2012 (Brain Neoplasms...) : The pro-apoptotic effect of GNA on U251 cells was shown to be mediated through inactivation of the Akt pathway, because GNA efficiently suppressed the expression level of EGFR and reduced the phosphorylation of Akt ( T308 ) and GSK3ß ( S9 )