Gene interactions and pathways from curated databases and text-mining

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GNAO1 — VEGFA

Pathways - manually collected, often from reviews:

  • NCI Pathway Database S1P3 pathway: VEGFR1 homodimer/VEGFA homodimer complex (FLT1-VEGFA) → S1P/S1P3/Gi complex (S1PR3-GNAI2_GNAI3_GNAO1_GNAO1_GNAZ_GNAI1) (transcription, activates)
    Fieber et al., Exp Cell Res 2006
    Evidence: mutant phenotype, assay, other species