◀ Back to PRL

GRP — PRL

Text-mined interactions from Literome

Houben et al., Endocrinology 1990 : The effect of the bombesin-like peptides, gastrin releasing peptide (GRP) and neuromedin-C ( NMC ), and the ranatensin-like peptides, neuromedin-B (NMB), neuromedin-B30 (NMB30), and neuromedin-B32 (NMB32), on pituitary GH and PRL release was studied in perifused anterior pituitary aggregate cell cultures from 9- to 12-week-old male rats cultured in serum-free defined medium supplemented with 0.05 nM T3 and 4 nM dexamethasone ( DEX )
Knigge et al., J Clin Endocrinol Metab 1987 : GRP had no effect on PRL or GH secretion
Matsushita et al., Proc Soc Exp Biol Med 1983 : Synthetic gastrin releasing peptide (GRP) injected intraventricularly ( 1 microgram/rat ), but not intravenously, suppressed rat prolactin (PRL) release induced by a Met-enkephalin analog, FK33-824 ( 10 micrograms/100 g body wt., iv ) ... In contrast, GRP did not suppress elevated plasma PRL levels sustained by a large dose of domperidone ( 10 micrograms/100 g body wt., iv ) ... These results suggest that GRP inhibits PRL secretion in the rat by acting through the brain to stimulate the dopaminergic mechanism
Kentroti et al., Brain Res Bull 1996 : The ability of gastrin releasing peptide to inhibit the release of growth hormone and prolactin by a hypothalamic mechanism has been previously reported
Di et al., Sheng Li Xue Bao 1997 (Pituitary Neoplasms...) : [ The effects of gastrin releasing peptide (GRP) and vasoactive intestinal polypeptide (VIP) on the prolactin (PRL) gene transcription of pitutitary PRL releasing tumor of rat ] ... The effects of gastrin releasing peptide (GRP) and vasoactive intestinal polypeptide (VIP) on the prolactin gene transcription of cultured pituitary of male Sprague-Dawley ( SD ) rats PRL releasing tumor ( PPRT ) ( induced by estradiol ) cells were studied