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Martinez et al., Cell Microbiol 2002
(Cystitis) :
Taken together, these data suggest that FimH mediated invasion is dependent on GTP binding protein activity that involves Cdc42 and PI 3-kinase activation probably upstream of Rac1
Zhang et al., J Biol Chem 1995
:
We have reported that platelets exposed to thrombin or thrombin receptor directed ligand activate phospholipase C and rapidly accumulate phosphatidylinositol ( 3,4,5 ) -trisphosphate ( PtdIns ( 3,4,5 ) P3 ) and phosphatidylinositol ( 3,4 ) -bisphosphate ( PtdIns ( 3,4 ) P2 ) as a function of the activation of phosphoinositide (PI) 3-kinases in a GTP binding protein dependent manner