Gene interactions and pathways from curated databases and text-mining

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HK2 — MYLIP

Text-mined interactions from Literome

Peschiaroli et al., Oncogene 2013 (Carcinoma, Squamous Cell...) : miR-143 regulates hexokinase 2 expression in cancer cells
Gregersen et al., BMC cancer 2012 (Colonic Neoplasms) : Furthermore, our results indicate that miR-143 mediated down-regulation of HK2 affects glucose metabolism in colon cancer cells ... We hypothesize that loss of miR-143 mediated repression of HK2 can promote glucose metabolism in cancer cells, contributing to the shift towards aerobic glycolysis observed in many tumors
Matkovich et al., Circ Res 2013 : miR-143 suppressed its direct cardiac mRNA target hexokinase 2 , but exhibited little indirect target regulation and did not regulate other cardiac microRNAs