Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — STAT1

Text-mined interactions from Literome

Sakatsume et al., Kidney Int 2000 (Glomerulonephritis) : Overexpression of Stat1-mutant lacking 35 C-terminal amino acids strongly suppressed the IFN-gamma induced signal transduction and inhibited the expression of MHC class II and CIITA genes in mesangial cells
Barrionuevo et al., Clin Exp Immunol 2003 (Chronic Disease...) : We demonstrate that IC induce a depletion not only on surface expressed but also on intracellular MHC class II content and that IC-induced down-regulation of MHC class II is not mediated by the inhibition of STAT-1 phosphorylation