Gene interactions and pathways from curated databases and text-mining

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HSPB3 — TNF

Text-mined interactions from Literome

Steenbergen et al., Am J Physiol Heart Circ Physiol 2003 (Cardiac Output, Low...) : Specifically, we found decreased expression of TNF-alpha- and NF-kappaB induced antiapoptotic genes such as growth arrest and DNA damage-inducible ( GADD ) 45beta, Flice inhibitory protein (FLIP), and TNF induced protein 3 ( A20 )
Bredel et al., J Clin Oncol 2006 (Glioblastoma) : Tumor necrosis factor-alpha induced protein 3 as a putative regulator of nuclear factor-kappaB mediated resistance to O6-alkylating agents in human glioblastomas ... Tumor necrosis factor-alpha induced protein 3 ( TNFAIP3 ) was identified as a new regulatory component of a putative cytoplasmic signaling cascade that mediates NF-kappaB activation in response to DNA damage caused by O6-alkylating agents
Boonyasrisawat et al., Diabetes 2007 (Coronary Artery Disease...) : A20 or tumor necrosis factor (TNF) induced protein 3 ( TNFAIP3 ) is a negative regulator of nuclear factor-kappaB (NF-kappaB)
Thomson et al., Nat Genet 2007 (Arthritis, Rheumatoid...) : This SNP maps to 6q23, between the genes oligodendrocyte lineage transcription factor 3 ( OLIG3 ) and tumor necrosis factor-alpha induced protein 3 ( TNFAIP3 )
Huang et al., Hypertension 2010 (Body Weight...) : A20 or tumor necrosis factor induced protein 3 is a negative regulator of nuclear factor kappaB signaling
Lippens et al., Cell Death Differ 2011 (Hyperplasia) : The ubiquitin editing enzyme A20 ( tumor necrosis factor-a induced protein 3 ) serves as a critical brake on nuclear factor ?B ( NF-?B ) signaling
Sisto et al., Histochem Cell Biol 2011 (Sjogren's Syndrome) : TNF-a induced protein 3 or TNFAIP3 is involved in the negative feedback regulation of nuclear factor-?B ( NF-?B ) signaling in response to specific pro-inflammatory stimuli in different cell types
Ben Hamad et al., Rheumatol Int 2012 (Arthritis, Rheumatoid...) : TNFAIP3 ( tumor necrosis factor , alpha induced protein 3 ) gene located in a region of genetic susceptibility in RA is an attractive candidate to be involved in autoimmunity disorders
Tejasvi et al., J Invest Dermatol 2012 (Psoriasis) : The tumor necrosis factor-alpha induced protein 3 ( TNFAIP3 ) gene has been associated with psoriasis, rheumatoid arthritis, type 1 diabetes mellitus, systemic lupus erythematosus, and celiac disease
Wang et al., Journal of transplantation 2011 : Induction of protective genes in the recipient ( e.g., heme oxygenase-1 (HO-1), A20/tumor necrosis factor alpha inducible protein3 ( tnfaip3 ), biliverdin reductase ( BVR ), Bcl2, and others ) or administration of one or more of the products of HO-1 to the donor, the islets themselves, and/or the recipient offers an alternative or synergistic approach to improve islet graft survival and function
Ross et al., Journal of inflammation research 2013 : The aim of this study was to examine the effect of a pulsed electromagnetic field on the production of inflammatory markers tumor necrosis factor (TNF), transcription factor nuclear factor kappa B (NFkB), and the expression of the A20 ( tumor necrosis factor-alpha induced protein 3 ), in an inflamed-cell model
Balkhi et al., Science signaling 2013 : The tumor suppressor A20 [ also known as TNFAIP3 ( tumor necrosis factor-a induced protein 3 ) ] inhibits an upstream activator of NF-?B and is often mutated in lymphomas