Swarbrick et al., Oncogene 2005
(Breast Neoplasms) :
These data indicate that in mammary epithelial cells, Id1 has cell cycle regulatory functions that are similar to those of c-Myc, and suggest that cyclin D1 may be involved in Id1 regulation of cell cycle progression
Ozeki et al., J Neurosci Res 2007
:
Blockage of the NF-kappaB activity with pyrrolidine dithiocarbamate ( PDTC ) or enhancement of the NF-kappaB activity with p65 ( a subunit of NF-kappaB ) in OC1 significantly inhibited or increased, respectively, the cell proliferation and transcription of cyclin D1 induced by Id1 Caldon et al., Cancer Res 2008
(Breast Neoplasms...) :
Id1 overexpression was unable to increase the volume of cyclin D1 ( -/- ) acini, indicating that Id1 is dependent on cyclin D1 for its proliferative effects
Tobin et al., BMC cancer 2011
(Breast Neoplasms...) :
It has previously been shown that silencing cyclin D1 increases the migratory capacity of MDA-MB-231 breast cancer cells with concomitant increase in ` inhibitor of differentiation 1' (ID1) gene expression