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ID1 — VEGFA

Text-mined interactions from Literome

Pammer et al., Endothelium : journal of endothelial cell research 2004 : Id1 was up-regulated by fluvastatin and serum, but not by VEGF and HGF
Ling et al., Carcinogenesis 2005 (Adenocarcinoma...) : Using prostate cancer cells ectopically transfected with the Id-1 gene, we found that upregulation of Id-1 induced VEGF secretion through activation of the VEGF gene transcription ... Downregulation of Id-1 , however, led to the suppression of VEGF secretion and its gene promoter activity
Lee et al., Clin Cancer Res 2006 (Carcinoma, Hepatocellular...) : Id-1 induced transcriptional activation of VEGF by stabilizing hypoxia-inducible factor-1alpha protein ... Down-regulation of Id-1 by antisense approach led to suppression of hypoxia-inducible factor-1alpha mediated VEGF production
Kim et al., Mol Cancer Res 2007 (MAP Kinase Signaling System) : Inhibitor of DNA binding 1 activates vascular endothelial growth factor through enhancing the stability and activity of hypoxia-inducible factor-1alpha ... Here, we show the cross talk between Id-1 and hypoxia-inducible factor-1alpha ( HIF-1alpha ), that Id-1 induces VEGF by enhancing the stability and activity of HIF-1alpha in human endothelial and breast cancer cells ... Although both the transcript and proteins levels of VEGF were induced by Id-1 , only the protein expression of HIF-1alpha was induced without transcriptional changes in both human umbilical endothelial cells and MCF7 breast cancer cells
Li et al., Mol Cell Biochem 2012 : Id1 was presented at low levels in EPCs, and was rapidly up-regulated by stimulation with vascular endothelial growth factor