Gene interactions and pathways from curated databases and text-mining

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IDDM14 — TNF

Text-mined interactions from Literome

Kulseng et al., Acta Diabetol 1999 (Diabetes Mellitus, Type 1...) : However, the role of soluble TNF receptors in insulin dependent diabetes mellitus ( type 1 DM ) is not clear
Green et al., Immunol Rev 1999 (Diabetes Mellitus, Type 1...) : Here we describe a new NOD model for analyzing the role of TNF-alpha in IDDM , TNF-alpha-NOD mice
Picarella et al., J Immunol 1993 (Diabetes Mellitus, Type 1...) : To understand the role of TNF in the regulation of inflammation and the development of autoimmune diseases such as insulin dependent diabetes mellitus , we produced transgenic mice in which the synthesis of murine TNF-alpha was directed by the rat insulin II promoter
Chosich et al., Autoimmunity 1994 (Diabetes Mellitus, Type 1) : To investigate a possible role for TNF in IDDM we compared endogenous TNF production in two lines of non-obese diabetic ( NOD ) mice, NOD/Lt and NOD/WEHI, that have a high and low incidence of diabetes, respectively
Winkler et al., Orv Hetil 1998 (Diabetes Mellitus...) : The present paper summarizes the data ( including the authors ' observations as well ) focusing on the potential role of TNF-alpha in the pathogenesis of obesity and non-insulin dependent diabetes mellitus : alteration of insulin receptor function, lipid metabolism, expression of sulphonylurea receptors, all of them suggested to be related to the TNF-alpha
Nilsson et al., Arterioscler Thromb Vasc Biol 1998 (Diabetes Mellitus, Type 2...) : The finding of an association between high plasma levels of TNF-alpha and several metabolic abnormalities characteristic for the insulin resistance syndrome suggests that TNF-alpha may be involved in the pathogenesis of non-insulin dependent diabetes mellitus