Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Hong et al., Mol Cell 2008 (Melanoma) : Cellular mTOR activation, by refeeding of amino acid deprived cells or by TSC2 shRNA, activated SGK1 and p27 phosphorylation at T157, and both were inhibited by short-term rapamycin treatment and by SGK1 shRNA
Shanmugasundaram et al., Oncogene 2013 (Carcinoma, Renal Cell...) : We also demonstrate a novel role for mTORC2 in the modulation of nuclear p27 levels
Lightell et al., The Ochsner journal 2013 : We conclude that diabetes is accompanied by a relative resistance to the effects of mTOR inhibition on VSMC proliferation through a loss of mTOR 's effects on p27 ( Kip1 ) levels