Rini et al., Cancer 2006
(Carcinoma, Renal Cell...) :
Based on potential additive or synergistic antitumor effects, interferon-alpha ( IFNalpha ) and celecoxib, an oral COX-2 inhibitor , were given to metastatic RCC patients in a Phase II trial
Cao et al., World J Gastroenterol 2008
(Carcinoma, Hepatocellular...) :
Inhibitory effect of interferon-alpha-2b on expression of cyclooxygenase-2 and vascular endothelial growth factor in human hepatocellular carcinoma inoculated in nude mice ... To evaluate the effects of interferon-alpha-2b ( IFN-alpha-2b ) on expression of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor ( VEGF ) in human hepatocellular carcinoma ( HCC ) inoculated in nude mice and to study the underlying mechanism of IFN-alpha-2b against HCC growth