Gene interactions and pathways from curated databases and text-mining

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IGF2R — TGFB1

Text-mined interactions from Literome

Wang et al., Radiother Oncol 1999 (Intestinal Diseases...) : Thus, we used a rat model of radiation enteropathy to examine the potential role of the M6P/IGF-II receptor in the in vivo regulation of TGF-beta1 activity and localization
Gray et al., Exp Cell Res 1999 (Carcinoma, Hepatocellular...) : Latent TGFbeta1 can be activated by the M6P/IGF2R
Moldovan et al., Arthritis Rheum 2000 (Osteoarthritis, Knee) : Plasmin and furin inhibitors and anti-M6P/IGF-2R reduced the levels of exogenous small latent TGFbeta1 complex induced collagenase 3 by 33 %, 95 %, and 76 %, respectively, but the cathepsin inhibitor had no effect
De Souza et al., Oncogene 1995 (Carcinoma, Hepatocellular...) : The mannose 6-phosphate/insulin-like growth factor II receptor ( M6P/IGFIIr ) is required for the activation of transforming growth factor beta , and previously we have found its expression to be significantly reduced in both rat and human hepatocellular carcinomas (HCCs)