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IGF2R — TGFB1
Text-mined interactions from Literome
Wang et al., Radiother Oncol 1999
(Intestinal Diseases...) :
Thus, we used a rat model of radiation enteropathy to examine the potential
role of the
M6P/IGF-II receptor in the in vivo regulation of
TGF-beta1 activity and localization
Gray et al., Exp Cell Res 1999
(Carcinoma, Hepatocellular...) :
Latent
TGFbeta1 can be
activated by the
M6P/IGF2R
Moldovan et al., Arthritis Rheum 2000
(Osteoarthritis, Knee) :
Plasmin and furin inhibitors and
anti-M6P/IGF-2R reduced the levels of exogenous small latent
TGFbeta1 complex induced collagenase 3 by 33 %, 95 %, and 76 %, respectively, but the cathepsin inhibitor had no effect
De Souza et al., Oncogene 1995
(Carcinoma, Hepatocellular...) :
The mannose
6-phosphate/insulin-like growth factor II receptor ( M6P/IGFIIr ) is
required for the activation of
transforming growth factor beta , and previously we have found its expression to be significantly reduced in both rat and human hepatocellular carcinomas (HCCs)