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IL1A — PRKAG1

Text-mined interactions from Literome

Łabuzek et al., Pharmacol Rep 2010 : Furthermore, the effects of metformin on the release of IL-1ß , IL-6, IL-10, TGF-ß, NO, and ROS as well as on the expression of arginase I, iNOS, NF-?B p65 and PGC-1a were not AMPK dependent , because pretreatment of LPS activated microglia with compound C, a pharmacological inhibitor of AMPK, did not reverse the effect of metformin
Villarroel et al., Diabetologia 2011 (Diabetic Retinopathy...) : Fenofibric acid prevented the activation of AMPK induced by IL-1ß and the hyperpermeability induced by IL-1ß was blocked by silencing AMPK
Kato et al., Cell Signal 2012 : IL-1 induced phosphorylation of AMPK-a ( Thr-172 ), which regulates AMPK activities, and acetyl-CoA carboxylase, a direct substrate of AMPK
Kondo et al., Arch Biochem Biophys 2013 : We previously reported that interleukin 1 (IL-1) stimulates the synthesis of interleukin 6 (IL-6) through activation of ERK and p38 MAP kinase in osteoblast-like MC3T3-E1 cells, and that AMP activated protein kinase (AMPK) negatively regulates the IL-1 induced IL-6 synthesis through I?B/NF-?B pathway ... SP600125 remarkably suppressed the IL-1 induced phosphorylation of both I?B and NF-?B, whereas SP600125 failed to affect the IL-1 induced phosphorylation of AMPK , STAT3 or Src
Kuroyanagi et al., Biochimie 2013 : We previously reported that interleukin-1 (IL-1) , a potent bone resorptive cytokine, stimulates the synthesis of interleukin-6 (IL-6) via activation of p44/p42 mitogen activated protein ( MAP ) kinase and p38 MAP kinase in osteoblast-like MC3T3-E1 cells, and that AMP activated protein kinase (AMPK) negatively regulates the IL-1 induced IL-6 synthesis through the inhibitor of ?B ( I?B ) /nuclear factor-?B ( NF-?B ) pathway ... On the other hand, EGCG failed to affect the IL-1 induced phosphorylation of p44/p42 MAP kinase, p38 MAP kinase and AMPK