Gene interactions and pathways from curated databases and text-mining

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IL1RAP — IRF6

Text-mined interactions from Literome

Pinteaux et al., J Neurochem 2002 : Bacterial lipopolysaccharide (LPS) caused increased expression of IL-1RI, IL-1RII and IL-1RAcP mRNAs, induced the release of IL-1beta, IL-6 and prostaglandin-E2 ( PGE2 ), and activated nuclear factor kappaB (NF-kappaB) and the mitogen activated protein kinases ( MAPKs ) p38, and extracellular signal regulated protein kinase ( ERK1/2 ), but not c-Jun N-terminal kinase (JNK) in microglial cultures
Saccani et al., Cytokine 1998 : Expression of IL-1R AcP in monocytes was less substantially affected by LPS