Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Cruz et al., J Leukoc Biol 2005 : We show that S6K2 is activated by IL-3 in the IL-3 dependent Ba/F3 cell line and that this is mediated by mTOR and its upstream activator PI-3K but not by the MAPK kinase/extracellular signal regulated kinase pathway
Sekulić et al., Cancer Res 2000 : In this study, we demonstrate that interleukin-3 stimulation induces a wortmannin-sensitive increase in mTOR kinase activity in a myeloid progenitor cell line
Ohtani et al., Blood 2008 (Leishmaniasis, Cutaneous) : Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide induced interleukin-12 production in dendritic cells