Bennett et al., Blood 2006
(Inflammation...) :
Thus, knock-down of RAX expression by 80 % using small interfering RNA ( siRNA ) prevents IFNgamma/tumor necrosis factor alpha (TNFalpha) induced PKR activation and eIF2alpha phosphorylation, IkappaB degradation, IRF-1 expression, and STAT1 phosphorylation, resulting in enhanced murine embryonic fibroblast (MEF) cell survival
Paun et al., J Biol Chem 2008
(Newcastle Disease) :
In addition, IRF-5 regulates TNFalpha but not type I interferon gene transcription in Newcastle disease virus infected peritoneal macrophages